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Thursday 7 June 2012

Stem cell storage: As priceless as your family's health

Stem cell storage is the cryopreservation of a potential graft, for use within the family. It is a preventive action, which may be of priceless value in the future, as priceless as your family's health.
Private storage keeps the valuable stem cells for medical use and seeks to resolve the histocompatibility problem. This problem makes allocation of a life-saving graft costly, time consuming and sometimes impossible, unless it has been stored at the moment of birth.
Storing your child's stem cells can only take place at the moment of birth and can guarantee immediate access to a graft:

- 100 % histocompatible with the infant, from who cord blood was collected
- 25 % possibility for 100% histocompatibility, for each sibling from the same biological parents
It must be made clear that the family has the exclusive legal power to recall the stem cells collected from the infant.

Store the optimal graft

In addition, it can be easily proven that newborn stem cells are the ideal graft for most of the cases. Apart from the fact that cord blood has already been used in 20000 transplant cases, there are specific clinical studies, which indicate that cord blood is at least as effective as bone marrow and in some cases superior, as source of stem cells. More precisely, the following have been observed:
Additional attributes of cord blood stem cells

In addition, we would like to mention about umbilicoplacental blood that:


  • its collection is easy, safe and painless for both mother and infant
  • there is no time delay to find an histocompatible donor in case of autologous transplantation
  • the use of stored stem cells when considered necessary, is immediate.
India's first private cord blood stem cell bank, 'Lifecell' has been launched in Chennai and recently set up in Hyderabad and Bangalore and all major cities.
But it is not only from embryos that stem cells can be gathered and used. There are three sources from which stem cells can be derived- embryonic, adult and umbilical cord.

Lifesaving umbilical cord stem cells.
The umbilical cord, connecting the foetus with the mother is cut at the time of delivery and discarded. Cord blood (the remaining blood in the umbilical cord) is full of 'stem cells' which is the origin of the body's immune and blood system.
Based on this and other successful transplants, doctors and medical researchers began to collect, freeze and store cord blood units at cord banks throughout the world to treat several ailments and save lives.
Research is also going on to treat diseases like stroke, Alzheimer's, multiplesclerosis, lupus and diabetes by transplanting cord blood stem cells.
A bank for cord blood stem cells.
Cord stem cell preservation consists of collecting the 'leftover' umbilical cord blood from the placenta and umbilical cord after the baby is delivered and the cord is cut.
This blood is sent to a bank where it is processed and preserved by freezing them in liquid nitrogen at a temperature of -195 degree celsius.
Many clinical studies showed that unrelated cord blood transplantation is safe and is an acceptable alternative to bone marrow transplantation for many patients. However, the studies also found that, as with bone marrow transplants, patients who receive cord blood from siblings or related donors generally have higher survival rates than those who receive cord blood from unrelated donors.
Researchers say that collecting and preserving a baby's cord blood stem cells would be a security blanket for the baby and his family members. In fact, it is estimated that the probability of a need for cord blood stem cells arising within a family is as high as 1/1,500.
Cord stem cell bank in India.
In this backdrop, the launch of a cord stem cell private bank in India assumes great significance. According to Dr Saranya, medical director of 'Lifecell', parents who are expecting a baby can register with the organisation by paying a onetime fee of Rs 59,900.
The family can preserve the cord blood cells from the umbilical cord for 21 years at the private bank, 'Lifecell'. Alternatively, they can pay a sum of Rs 29,000 and a yearly fee of Rs 2,900 for storing the cells for 21 years.


Benefits and advantages of Stem Cell storage.

  • Protection for the entire family - Cord blood stem cells are not just for your baby - but are an investment for the whole family. A genetically unique resource, your baby's stem cells have a 25% probability of being a perfect match for a sibling - should he or she ever need a stem cell transplant. Clinical studies have also proven that stem cell transplants are twice as successful when the stem cells come from a family member rather than from a non-relative.
  • A resource kept ready - When you bank your baby's cord blood stem cells with a private bank, you can enjoy the peace of mind of knowing that your baby's stem cells are available- should the need ever arise.
  • once-in-a-lifetime opportunity to preserve a biological resource that could be a lifesaver for your child or other family members.
  • life-saving alternative to bone marrow transplants. Doctors have increasingly turned to cord blood stem cells as there is a lower probability of graft vs. host disease (GVHD) and a greater likelihood of finding an appropriate tissue type match.
  • Cord blood is easy to retrieve and is readily available whenever it is needed, unlike bone marrow for example, where it is harder to find a donor matching your HLA type.
  • There are many benefits in storing stem cells harvested from cord or adult peripheral (circulating) blood. Results from both animal studies and early human clinical trials indicate that they have significant capabilities for growth, repair, and regeneration of damaged cells and tissues in the body. Within the last decade alone, science has revealed many benefits of adult stem cells and cord blood stem cells, resulting from research done in both animal studies and early human clinical trials. This stem cell research indicates that they have significant capabilities for growth, repair, and regeneration of damaged cells and tissues in the body.
If the public cord blood stem cell bank becomes a reality, it would save the lives of many patients in India.



(Cost mentioned is approximate cost calculated at the time of Bank establishment)
Source : http://www.stemcellsbank.ro ,http://www.assureimmune.com, http://www.lifecellinternational.com & Rediff.com

Saturday 2 June 2012

What is the need of vehicle (4Wheeler) moving backwards without Driver Concern?

Let me put up a small question among our self, many of us are very mush interested about cars. Posh cars, family cars, SUV's, recently LUV's etc etc. In this let us think about this.. Do we need the mechanism of car movement towards backward when its in neutral. I say NO, Moving back is required but without driver concern. Then what can we do so.. Yes here is the solution. When in an normal operation their is no need of a vehicle moving backwards. Ex : In a steep or in a slant road while the vehicle is in halt. if its out of gear it moves back upon steep.
what actually i propose is that their should be a gear/switch such that backward movement (mechanical & free movement) should be activated only upon operation of that gear. unless it should be kept moving forward or neutral. it advantages in traffic where the halted vehicle has chance of striking the prior vehicle in the action of gear shift. Its more useful for the New drivers who learn driving in steep roads which may reduce the risk of vehicle moving back in gear shift operation. Simple Change isn't...

If you have any Doubts or questions. Don't forget to ask.. Pass on your comments...

Saturday 12 May 2012

Simple Egg Chicken Roll


One day My Brother forced me to prepare some thing Delicious as it was boring for him and he was hungry.  It was Sunday so thought of preparing chicken roles. Searched Google and found few recipe which was difficult to get all those ingredients at that instant. So i modified the process of Roles into simple without compromising with taste and the recipe is here......

Simple Egg Chicken Roll Ingredients:

  • All purpose flour
  • Chicken
  • Eggs
  • Oil
  • Salt (as per taste)
  • Chopped Onion
  • Sliced Tomato 
  • Chicken Masala

Dressing(If Required)

  • Soya sauce (2tbsp)
  • Chili sauce (2tbsp)
  • Tomato sauce (3tbsp)

How to Make Chicken Egg Rolls:

  • Take a pan and add oil, when it gets hot  Fry Chopped Onions till it turn Golden brown and then add sliced tomato and fry it for 3 minutes.
  • Add Cleaned chicken pieces into pan and little water to it.
  • Boil for 5 minutes and then add Chicken masala(as per required) salt and Chilly powder(green chilly).
  • Heat till the chicken is cooked and keep it aside. 
  • In the meantime you can make the dough using all purpose flour.
  • Take the flour and add ¼ cup of water and mix it well by hand, if you need more water then add it but do not make the dough very soft by adding more water.
  • Make chapati or roti using this dough, this normally looks like tortillas.
  • Take a pan, when it becomes hot add the chapati. After 2 minutes turn it over and add 1/2tbsp oil to it.
  • Add the beaten egg and again turn it to other side, cook it in medium heat for 2-3 minutes.
  • Take the egg chapati out and roll it using chicken.
  • Along with chicken Onions can be used.
  • Other vegetable like capsicum, cabbage etc can be used for different flavors (if required)
  • Roll it with the foil/paper and serve it.

Dressing 

  • Use sauces to Dress the role depending upon the taste.
  • Sauce  can be used while rolling the egg chapati with chicken and onions.



The delicious Indian egg chicken rolls in the picture, I hope you will also like it. If you happen to cook it at home then don’t miss to write your experience here as comments.









Saturday 28 April 2012

Dual Mileage ....

 

Why cant Motor Bikes have two types of mileage capacity?????



Here is the concept...


A single bike can have two modes of switching for mileage and for power/Speed. For example changing the CC of engine as required. that's only an example.
Taking all other factors into consideration which impacts mileage in vehicle it can be implemented.Of course the cost will be high but still its worth for the most of bikers. In this concept their is option to switch between power and performance as required, the mechanism is that both cylinders has same engine and gear system but operation depends on rider. If the situation demands for mileage then rider can switch to Lower CC engine if not he can be in higher CC. As we all know lower  CC engines provide good Mileage as higher cc engine offers good power and speed.

Let us elaborate the example.

The biker who rides bike in highway needs more power/speed as their wont be any obstacles and can keep going in constant speed without frequent use of Clutch and gear. where as the same rider enters the congestion area like city limits then higher CC engines offers poor performance where as rider as to use clutch and breaks frequently. so at this instance he can switch back to lower cc engine which can offer good performance.


Need of sports Bike.

We know sports bikes come starting with 220cc (Pulsar 220) and ranges til < 1000cc(The Rapom V8). But in reality do we need it daily. Ofcourse answer is no. sports bikes are only for passion (depends). where we cant give up too. passion is also required. In this concept the bike designed with dual mileage(cylinder) can act as sports bike aswel  domestic. when riders feels like sporting he can switch to speed and power if not he can use the bike economically(considering fuel cost)

So it can be concluded that considering Fuel cost and its importance along with youth passion towards bikes the concept described above will contribute desirable changes to the current system. Their needs to be made some changes which suits the commercial market. 


(Concept by : UdayBM from Team Twlight)

Saturday 29 October 2011

Sensors In Future Mobile Phones: Altitude, Emotion and More

The New York Times Nick Bilton spoke with Benedetto Vigna, general manager of the MEMS division of STMicroelectronics, about what kinds of sensors we might be seeing in the next generation of mobile phones.

The iPhone presently uses a number of sensors such as GPS, accelerometer, gyroscope, and digital compass. These sensors have found to be quite useful in various social applications and games.

The next generation of sensors could include additional location providing ones, such as an altimeter:
Mr. Vigna said the next smartphones would have altimeter sensors that would be able to detect your elevation. “These sensors will tell people what floor they are on in a building, or could be used to more precisely determine where you are in relation to your friends on a location-based service,” he said.
Other possibilities include heart monitors, perspiration/mood sensors, and temperature/humidity sensors. The new sensors could even be used in games to determine excitement or emotion during gameplay.

Meanwhile, a combination of factors (phone position, and other patterns) could be used to identify the user for security purposes. After you use a new phone for a short period of time, it will start to learn your patterns and automatically lock or unlock the phone accordingly. This could be used for more secure banking too.